US EditionArtemisinin Partial Resistance in Ugandan Children
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Artemisinin Partial Resistance in Ugandan Children
To the Editor The article by Dr Henrici and colleagues notes an urgent problem of artemisinin combination therapies that induced artemisinin partial resistance in 110 Ugandan children. Resistance was promoted by Pfkelch13 gene variations in Plasmodium falciparum. Even before the 2015 Nobel Prize for artemisinin’s discovery and isolation from the plant Artemisia annua, reports of resistance arose in Cambodia and Thailand. It was inevitable that r…
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