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Are RIPTACs the Small Molecule Answers to ADCs?

Summary by Drug Hunter
This article provides a brief overview of RIPTACs™, a unique heterobifunctional small molecule modality capable of targeting and selectively killing cells via the formation of a ternary complex between a cell-type specific TP (target protein), the RIPTAC™ molecule, and a pan-essential effector protein (EP) that is required for cell survival. We also highlight Halda’s development of HLD-0915, a first-to-clinic RIPTAC™ therapeutic, targeting mCRPC…
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Drug HunterDrug Hunter

Are RIPTACs the Small Molecule Answers to ADCs?

This article provides a brief overview of RIPTACs™, a unique heterobifunctional small molecule modality capable of targeting and selectively killing cells via the formation of a ternary complex between a cell-type specific TP (target protein), the RIPTAC™ molecule, and a pan-essential effector protein (EP) that is required for cell survival. We also highlight Halda’s development of HLD-0915, a first-to-clinic RIPTAC™ therapeutic, targeting mCRPC…

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Drug Hunter broke the news in on Friday, June 6, 2025.
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