AI-Designed Proteins Boost Immune Cell Production, Can Enhance Immunotherapy

AI-Designed Proteins Boost Immune Cell Production, Can Enhance Immunotherapy

A team of researchers led by scientists from Harvard Medical School and Boston Children’s Hospital has harnessed AI to design synthetic proteins that activate a key immune pathway. This is aimed at enabling large-scale generation of T cells.  The research shows how AI-powered protein engineering could unlock new possibilities in cancer treatment and vaccine development. At the core of this innovation is the Notch signalling pathway, a critical c…

AI-Powered Protein Design Opens Doors to New T-Cell Based Immunotherapies

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development and function.