US EditionAfrica CDC Declares End to Mpox As Continental Health Emergency
Cases declined by 40% and deaths by 60% after $1 billion in funding and 5 million vaccine doses, marking a shift to sustained prevention and elimination efforts.
- On Friday, Dr Jean Kaseya, Director General, Africa Centres for Disease Control and Prevention , announced lifting Mpox as a Public Health Emergency of Continental Security following the Africa CDC Emergency Consultative Group's recommendation.
- The PHECS stemmed from Africa CDC's August 2024 declaration after 80,276 suspected cases and 1,340 deaths, more than five times cases and double deaths versus 2023.
- Operating through the IMST, co-led by Africa CDC and the World Health Organization , the response mobilised over $1 billion in financing, expanded genomic sequencing more than ten-fold, and deployed over 5 million Mpox vaccine doses across 16 countries.
- Between early 2025 and late 2025, suspected Mpox cases declined by 40% and confirmed cases by 60%, with the case fatality rate falling from 2% to 0.6%, while the DRC accounted for 96% of cases and 97% of deaths.
- To consolidate gains, Africa CDC will launch a Mpox Transition Roadmap with WHO, warning Mpox remains endemic and prioritizing vaccination, local vaccine manufacturing, and lessons for other epidemic-prone diseases.
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According to WHO, 78 per cent of the recorded cases of mpox in the world were in Africa. Between January 2025 and January 2026, some 44,500 cases (including 198 deaths) were recorded in 29 countries on the continent, the most affected being the DRC, Guinea and Madagascar.
According to the latest data from the agency, more than 224,000 cases have been registered since the beginning of 2024 in 32 countries on the continent.
Africa: Mpox No Longer Public Health Emergency
Africa has officially lifted Mpox as a Public Health Emergency of Continental Security following recommendations from the Africa CDC Emergency Consultative Group. The decision highlights the continent's strengthened health security, effective leadership, regional cooperation, and successful international partnerships in managing complex public health challenges.
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