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Japanese Team Starts Final-Stage Trial for iPS Drug to Treat Alzheimer's

  • A new review led by a University of Nevada expert in 2025 identified 182 clinical trials assessing 138 potential Alzheimer's drugs worldwide.
  • This rise of 11% from the previous year reflects growing focus on diverse treatments, including repurposed drugs originally for diabetes and multiple sclerosis.
  • Researchers at the University of Virginia found that blocking the immune molecule STING may reduce Alzheimer's hallmarks, suggesting new drug targets despite potential infection risks.
  • Experts highlight that recent advances, such as lecanemab and donanemab, modify disease progression and enable earlier treatment, with hope for more effective drugs within 10 to 15 years.
  • Together, these developments imply that combination therapies tailored by diagnosis could improve outcomes and lead to prevention strategies for Alzheimer's in the future.
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PsyBlog broke the news in on Monday, June 2, 2025.
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