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World's tiniest pacemaker is smaller than grain of rice

  • Northwestern University engineers developed and unveiled the world's smallest pacemaker, smaller than a grain of rice, in a study published on Wednesday in Nature.
  • The device addresses risks of traditional temporary pacemakers, which require wires sewn onto the heart and removal that can cause rare but lethal complications.
  • The pacemaker is inserted via catheter or syringe, placed in or on the heart, and activated wirelessly by a patch worn on the chest that emits light pulses to control rhythm.
  • About 40,000 U.S. Babies are born yearly with heart defects, many needing temporary pacing post-surgery, and the device designed to dissolve after use may help infants and adults, according to researchers.
  • Researchers plan to seek FDA approval and start human trials, believing the technology could transform short-term cardiac pacing if clinical results confirm its safety and effectiveness.
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Engineers develop tiny pacemaker, smaller than a grain of rice

A new, tiny pacemaker — smaller than a grain of rice — developed at Northwestern University could play a sizable role in the future of medicine, according to the engineers who developed it. Researchers unveiled the device, which they say is the smallest pacemaker in the world, in a study published Wednesday in the peer-reviewed journal Nature. Though the device is still years away from being used in humans, it could eventually be useful for infa…

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Nature broke the news in United Kingdom on Wednesday, April 2, 2025.
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