US EditionDrug Effective Against Early Migraine Symptoms
- Researchers reported on May 12, 2025, that the drug ubrogepant reduces early migraine symptoms when taken one to six hours before headache onset.
- This study followed earlier FDA approval in 2019 and existing evidence showing ubrogepant’s effectiveness in relieving headache pain within two hours.
- Ubrogepant significantly decreased light sensitivity by 72% and fatigue by 85%, and patients also reported improved concentration despite impending migraines.
- Dr. Peter Goadsby, co-author of the study and neuroscientist at King’s College London, highlighted that prodrome symptoms have been largely overlooked and stressed the need to take the medication before the headache begins in order to effectively prevent these early signs.
- The findings suggest that training patients to recognize early migraine signs could help them use ubrogepant effectively to reduce disabling prodrome symptoms.
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Migraine drug eases early symptoms before headache strikes
A migraine drug commonly used to treat headache pain may also alleviate the early, non-pain symptoms that often precede a migraine attack, according to research based on the results of a large clinical trial published in Nature Medicine. Although there is a paucity of headache studies, the World Health Organisation says about 10-15% of all adults experience migraine, and in Australia, it’s been estimated that migraines affect 5 million people. T…
·Washington, United States
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Drug Effective Against Early Migraine Symptoms
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