US EditionA genomic view of DNA damage in chemotherapy
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A genomic view of DNA damage in chemotherapy
Seventeen of 23 individuals exposed to chemotherapy had far more genetic mutations than could be explained by normal aging. Even more revealing was the discovery of eight unique mutational signatures that were found only in the chemotherapy group. While some of these fingerprints matched the known damage profiles of certain chemo drugs, four of them were entirely new to science, uncovering previously unknown ways these treatments can alter our D…
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