3S-DB Identifies an RNA Repository Facilitating Stop Codon Readthrough for Selenocysteine Insertion and Selenoproteome Expansion
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3S-DB Identifies an RNA Repository Facilitating Stop Codon Readthrough for Selenocysteine Insertion and Selenoproteome Expansion
Selenoproteins are proteins that contain selenocysteine (Sec, U), the 21st amino acid, whose highly reactive selenol group makes these proteins essential for redox regulation. Sec is incorporated via a stop codon readthrough mechanism—a widespread, functionally essential, and tightly reg...
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