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Medford, Massachusetts · MedfordResearchers have found a surprising connection between a fungus associated with alcohol use disorder and the brain’s dopamine reward pathway. Published in the journal mBio, the study describes, in mice, how an overgrowth of Candida albicans—a fungus that naturally resides in the human gut—increases levels of inflammatory molecules called PGE2 that can cross the blood-brain barrier and affect the desire for alcohol. PGE2, short for prostaglandin …See the Story
