When binding isn’t enough: Predicting TF activity through genomic neighborhoods
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1 Articles
When binding isn’t enough: Predicting TF activity through genomic neighborhoods
Transcriptional regulation is fundamental for coordinating cellular activities in response to developmental programs and environmental cues. Certain transcription factors (TFs) control the expression of hundreds of genes and are thus considered especially important — these are referred to as master regulators. However, predicting the regulatory activity of a TF remains challenging. Source
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