Long COVID: Major Findings, Mechanisms and Recommendations
UNITED STATES, JUL 11 – Researchers warn that cuts to National Institutes of Health funding and shuttered programs threaten progress in understanding and treating long COVID and future pandemics.
- Jody Croft, a 42-year-old mother of three from Cameron Park, has suffered severe long COVID symptoms including brain fog, insomnia, and hallucinations for seven months.
- Her condition followed a mild initial COVID case and is primarily managed through primary care with referrals to neurologists and sleep specialists as needed.
- Long COVID shares features with myalgic encephalomyelitis/chronic fatigue syndrome , with a 2024 meta-analysis finding about half of long COVID patients develop ME/CFS symptoms.
- The NIH RECOVER COVID Initiative tracks nearly 15,000 adult patients across 83 sites, while experts emphasize repurposing existing drugs for treatment rather than developing new medications.
- Despite ongoing infections and probable future pandemics, experts warn preparedness is insufficient due to cuts in research funding, politicized public health, and strained healthcare infrastructure.
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Long COVID: major findings, mechanisms and recommendations
Long COVID is an often debilitating illness that occurs in at least 10% of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms have been identified with impacts on multiple organ systems. At least 65 million individuals worldwide are estimated to have long COVID, with cases increasing daily. Biomedical research has made substantial progress in identifying various pathophysiological changes and risk fac…
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