What Channel Is Rams vs 49ers Game on TV Tonight? TNF Start Time, NFL Schedule, Streaming
The 49ers overcame multiple injuries and won 26-23 in overtime with Eddy Piñeiro’s decisive field goal, improving to 4-1 and taking sole NFC West lead, officials said.
- On Oct. 2, 2025, the San Francisco 49ers and Los Angeles Rams will kickoff at 8:15 p.m. ET at SoFi Stadium, streaming nationally on Amazon Prime Video and NFL+ with local simulcasts.
- With NFC West parity high, this matchup hands the winner a short-term division lead as both the San Francisco 49ers and Los Angeles Rams enter NFL Week 5 tied at 3-1.
- Listed inactives show the 49ers' injury issues going into the game with Brock Purdy, George Kittle, Jauan Jennings and Ricky Pearsall all sidelined, while Al Michaels, Kirk Herbstreit and Kaylee Hartung call the game.
- ESPN's model projects the Rams as slight favorites with a 57.2% win probability, and a victory moves the winner to 4-1 with an early NFC West edge.
- In a recent chapter of the rivalry, the 49ers prevailed 26-23 in overtime with Eddy Piñeiro's field goal before 73,652 fans at SoFi Stadium.
85 Articles
85 Articles

Swanson: Rams look nothing like Super Bowl contenders in loss to 49ers
INGLEWOOD — Imagine if plucking daisy petals actually determined your team’s fate: The Rams are Super Bowl contenders. The Rams are not Super Bowl contenders. The Rams are Super Bowl contenders. The Rams are not Super Bowl contenders … they do have what it takes; they don’t. On a short week against the rival San Francisco 49ers, the Rams didn’t pass the smell test. They are not Super Bowl contenders. Not unless they improve in every phase of pla…

What the 49ers said after beating the Rams in overtime
The 49ers are 3-0 in the NFC West after going on the road and beating the Rams 26-23 in overtime on a short week in Los Angeles. A fourth-and-1 stop from their own 11-yard line sealed the win after the last time in the red zone, Alfred Collins prevented a go-ahead touchdown by Kyren Williams when he punched the ball out at the 1. Mac Jones, starting in place of Brock Purdy and hobbled by a knee injury himself, was 33-of-49 for 342 yards and two …

4th-down stop in OT seals 49ers' victory over Rams
Eddy Pineiro kicked a 41-yard field goal and the San Francisco defense stuffed the Rams on fourth down later in overtime as the 49ers notched a 26-23 win over Los Angeles on Thursday night at Inglewood, Calif.
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