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Warning of 'Gastrointestinal Adverse Events' in Children Taking Weight-Loss Jabs

Studies involving 1,402 children show GLP-1 agonists significantly improve weight and blood sugar control in obese youths despite increased gastrointestinal side effects.

  • Researchers suggest weight-loss injections like GLP-1 agonists could help children aged six to 17 with obesity or type 2 diabetes.
  • Recent NHS data reveals that 22.1% of Year 6 students were classified as obese during 2023/24, marking a slight decrease from 22.7% the previous year.
  • A meta-analysis of 18 trials involving 1,402 children showed these drugs significantly improved weight and blood sugar control but increased gastrointestinal side effects.
  • Researchers emphasized the need for extended follow-up periods and additional practical studies to better determine the long-term impact of GLP-1 receptor agonists on children.
  • NHS prescriptions have strict criteria requiring in-person checks, and while these drugs are approved only for adults, their broader use in children depends on further evidence.
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The Independent (US) broke the news in United States on Monday, September 15, 2025.
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