US EditionWeight-loss drugs cut alcohol intake by almost two-thirds, research in Ireland suggests
- Researchers from University College Dublin studied 262 obese adults prescribed liraglutide or semaglutide in Dublin clinics who reduced alcohol intake over four months.
- The study followed patients with varying drinking levels, confirming none increased consumption, while regular drinkers reduced intake by nearly 70%, comparable to nalmefene.
- GLP-1 analogs, originally developed for obesity, appear to curb alcohol cravings via subcortical brain areas, though the exact mechanism remains under investigation.
- Average weekly alcohol intake fell from 11.3 to 4.3 units overall, with regular drinkers decreasing from 23.2 to 7.8 units, and patients described the effects as 'effortless.'
- The findings suggest weight-loss GLP-1 drugs could offer a novel aid for reducing alcohol consumption, but larger trials are needed to confirm this potential benefit.
19 Articles
19 Articles
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Weight-loss drugs cut alcohol intake by almost two-thirds, research in Ireland suggests
Individuals who take liraglutide or semaglutide for weight loss reduce their alcohol consumption by almost two-thirds in four months, new research presented at the European Congress on Obesity (ECO 2025) has found.
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