US EditionWeight-loss drugs cut alcohol intake by almost two-thirds, research in Ireland suggests
- A team of researchers in Dublin led by a professor from University College Dublin examined 262 obese adults who were treated with GLP-1 medications over a period of four months.
- They investigated alcohol consumption due to anecdotal reports of reduced drinking during weight-loss treatments with GLP-1 analogs like liraglutide and semaglutide.
- The study found average weekly alcohol intake fell from 11.3 to 4.3 units, a nearly two-thirds decrease, with regular drinkers reducing from 23.2 to 7.8 units.
- Professor le Roux noted the 68% reduction was comparable to nalmefene, an approved European alcohol disorder drug, and patients described the effect as 'effortless'.
- While the exact mechanism remains under study, the findings suggest GLP-1 medications may curb alcohol cravings and offer a potential treatment for alcohol use disorder pending larger trials.
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20 Articles
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