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Volunteers Lose Up to 25% Body Weight in High-Dose Wegovy Trials

A 7.2mg semaglutide dose led 33% of participants to lose 25% or more body weight, doubling the rate seen with the standard dose, with mostly mild gastrointestinal side effects.

Summary by Science Alert
A higher dose of the weight loss drug semaglutide (better known by its brand name Wegovy) may help people lose up to 25% of their body weight – without the risk of severe side effects.

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The Conversation broke the news in on Tuesday, September 16, 2025.
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