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Weight loss and diabetes jabs linked to potentially fatal side effect

  • The MHRA and Genomics England have launched the Yellow Card Biobank project to investigate pancreatitis cases linked to GLP-1 medicines in the UK.
  • This investigation follows hundreds of reports of acute and chronic pancreatitis among users of GLP-1 drugs, including Mounjaro, Wegovy, and Ozempic, some involving fatalities.
  • The MHRA is urging individuals hospitalized with acute pancreatitis while taking GLP-1 medicines to report via the Yellow Card scheme and provide saliva samples for genetic analysis.
  • Professor Matt Brown stated that GLP-1 medicines carry risks of serious side effects but many adverse reactions may have genetic causes allowing safer, personalised treatments.
  • The study seeks to identify patients with a genetic predisposition to medication side effects, aiming to prevent harmful reactions that are estimated to result in over £2.2 billion in annual hospital expenses for the NHS.
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ITV broke the news in London, United Kingdom on Wednesday, June 25, 2025.
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