BCRF-Backed Study Identifies Process Linked to Drug Resistance in Breast Cancer | Breast Cancer Research Foundation
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An international scientific team from the University of Vigo (UVigo) has discovered a new molecular mechanism capable of restricting the ability of tumor cells to repair their DNA, the main form of defense against drugs, reports the aforementioned academic center on Wednesday. The research, the result of more than seven years of work and published in the scientific journal Nature Communications, identifies the protein conexin 43 as a new and pow…
BCRF-Backed Study Identifies Process Linked to Drug Resistance in Breast Cancer | Breast Cancer Research Foundation
Dr. Sarat Chandarlapaty and team showed that a known family of enzymes that play an important role in how our bodies respond to an infection are also linked to breast cancer drug resistanceBreast cancer is often treated with hormone therapy (also known as endocrine therapy) and other targeted drugs like CDK4/6 or HER2 inhibitors. Many cancers respond well to these treatments, but for reasons we don’t fully understand yet, they can adapt and stop…
Researchers at the Center for Research in Nanomaterials and Biomedicine (CINBIO) of the University of Vigo, led by María Mayán, have discovered a new molecular mechanism capable of restricting the ability of tumor cells to prepare their DNA, one of the main forms of defense against drugs.
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