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US progesterone supplies tighten as menopause treatment demand grows
Clinicians and pharmacists say intermittent oral progesterone shortages are delaying treatment for patients as demand rises for menopause and fertility care.
U.S. progesterone supplies are tightening, with clinicians reporting intermittent shortages of oral versions used in fertility and menopause treatments as demand for hormone replacement therapy has surged.
Demand for hormone replacement therapy climbed sharply since the Food and Drug Administration removed a long-standing safety warning, while philanthropist Melinda French Gates is donating $215 million to improve women's health.
New research from Northwestern University found women who experienced menopause before age 40 face a 40 per cent higher risk of heart attack, underscoring the need for specialized care.
With standard supplies limited, some patients are turning to compounding pharmacies for progesterone, though the American Society of Health-System Pharmacists warns against using compounded products lacking strict FDA-approved regulation.
Manufacturers including Teva and Dr. Reddy's face ongoing delays, yet the Food and Drug Administration is working with producers to ensure supplies eventually meet surging demand for patient prescriptions.