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Super Bowl LXI Odds: 49ers, Bills Lead the Way After Week 6 - Bleacher Nation

The San Francisco 49ers are the last unbeaten team in the NFL, and the Super Bowl LXI odds finally treat them that way. After a 23-17 win over Washington on Monday night, San Francisco sits at +540 at DraftKings. That is a clear step ahead of everyone else. The Buffalo Bills and Kansas City Chiefs are tied right behind at +750. A week ago the top of this board was a four-team logjam. Now there is a favorite. Below you will find the full top of t…

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Bleacher Nation | Chicago Cubs News, Rumors, and Commentary… broke the news on Tuesday, October 20, 2026.
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