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UCSD takes detailed look at how space flight accelerates aging

UC San Diego researchers observed accelerated aging signs in astronauts' blood stem cells during 30-45 day space missions, with partial reversal after returning to Earth, aiding aging and disease research.

  • This month, University of California, San Diego researchers reported that space flight accelerates aging in blood and immune system stem cells, tracking these changes in real time aboard the International Space Station; findings appeared in the journal Cell Stem Cell.
  • Research has linked microgravity and cosmic galactic radiation during spaceflight to accelerated molecular aging in blood stem cells, Dr. Catriona Jamieson said, aiding astronaut health and human aging research.
  • After 32 to 45 days in orbit, blood-forming hematopoietic stem and progenitor cells showed aging hallmarks, losing regenerative ability and gaining DNA damage, tracked by automated AI-driven imaging on four SpaceX supply missions.
  • Returned space-exposed cells showed some damage reversed in a healthy environment, prompting UC San Diego researchers to continue studying astronauts and explore applications for aging and cancer research on Earth.
  • Nanobioreactors and AI-powered imaging tools enabled UCSD and Space Tango, a for-profit space research company, to study stem cell resilience during the SpaceX resupply mission that launched last month, building on NASA's Twins Study.
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Space Travel Accelerates Cellular Aging, Researchers Say

·New York, United States
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Times of San Diego broke the news in San Diego County, United States on Sunday, September 7, 2025.
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