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Tobacco Remains Top Cause of Fatal Cancer, Despite Lower Smoking Rates

Lung cancer causes over 80% of tobacco-related deaths in the U.S. amid disparities in screening and cessation, especially in regions with weaker tobacco control policies.

  • Despite declines in smoking, the American Cancer Society's U.S. Tobacco Atlas reports tobacco remains the leading preventable cause of cancer death in the U.S., with adult smoking dropping from 42% in 1965 to 11% in 2023.
  • Experts warn that persistent disparities in tobacco use and disease affect racial minorities, people with disabilities, LGBTQ+ individuals, and lower-income, less-educated groups, the report says.
  • Data show major gaps in screening and cessation use, with only 18% of eligible current or former smokers up to date in 2022 and lowest rates in Southern States and the Midwest, despite tobacco causing more than 80% of lung cancer deaths, the report says.
  • The report urges stronger state and federal policies to address inequities, with American Cancer Society leadership framing the U.S. Tobacco Atlas as a call to action for policymakers.
  • More than 1.6 million youth e-cigarette users prefer flavored e-cigarette products, while smokers attempting to quit surged to 62% in 2022, the report says.
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Tobacco Still Top Cancer Killer, Despite Falling Smoking Rates

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·Calhoun, United States
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The American Cancer Society (ACS) released the U.S. Tobacco Atlas report on Monday (November 3), stating that "smoking is a major risk factor for lung cancer, but in 2022 only 18.1% of eligible current or former smokers received the latest lung cancer screening."

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Medical Xpress broke the news in on Tuesday, November 4, 2025.
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