Cytomegalovirus Can Cause Permanent Birth Defects

Cytomegalovirus can cause permanent birth defects

Cytomegalovirus (CMV) recently caused a 2-month-old girl in Pennsylvania to suffer severe hearing loss after it was passed to her in the womb. While the virus can exist in a person for life without showing any symptoms, it can also cause permanent disability in infants. Researchers are looking to create a vaccine for the disease, but it has proven tricky.What is CMV?CMV is a common herpes virus. More than half of adults have been infected with C…

Multi-antigenic human cytomegalovirus mRNA vaccines that elicit potent humoral and cell-mediated immunity

A cytomegalovirus (CMV) vaccine that is effective at preventing congenital infection and reducing CMV disease in transplant patients remains a high pr…

The GATE Glycoprotein Complex Enhances Human Cytomegalovirus Entry in Endothelial Cells

Researchers identified a distinct glycoprotein H complex that is abundant on human cytomegalovirus virions and enhances infection of endothelial cells. [Nature Microbiology] Abstract