Leonardo da Vinci's Genetic Profile Advances with DNA and Lineage Breakthroughs
- On May 22, 2025, Alessandro Vezzosi and Agnese Sabato published Genealogy and Genetics for Leonardo’s DNA, tracing da Vinci’s family tree in Vinci, Italy.
- The publication follows 30 years of international genetic research aiming to reconstruct da Vinci’s lineage amid the absence of confirmed DNA from him.
- The book details a family tree spanning 21 generations and over 400 individuals, revealing 15 male-line descendants linked to da Vinci’s father and half-brother.
- Vezzosi explained that the project aims to trace the Da Vinci family tree through to modern times to support scientific analysis of Leonardo’s DNA.
- This work supports efforts to recover Leonardo’s DNA and better understand his creativity, vision, health, and death, though genetic proof remains unconfirmed.
32 Articles
32 Articles
Researchers have been trying to decipher Leonardo Da Vinci's DNA for 30 years, and now they've been able to find six people who share genes with him.
Da Vinci’s Bloodline Confirmed as Scientists Trace DNA in Living Descendants
Leonardo Da Vinci and Mona Lisa Painting. Credit: Leonardo da Vinci via sohu.com / Wikimedia Commons / United States Public Domain A team of international researchers has confirmed the male bloodline of Leonardo da Vinci by tracing his DNA in living descendants. The discovery marks a breakthrough in a decades-long investigation into the life and legacy of the Renaissance master. The findings are featured in a newly released book that presents th…
Dalmatio Vinci is the oldest of the direct descendants - just discovered thanks to the examination of the DNA - of the genius: airplanes, go karts, boat engines, cameras: I invented everything, and I also went on TV from Bonolis. A wish? I would like to go on Leonardo's tomb.


With the help of DNA analyses, international researchers have identified five descendants of da Vinci.
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