Testing Is Underway on Vaccines to Intercept Brewing Colon Cancer Before It Takes Root
Early trial data showed the shots boosted tumor-fighting T cells and left participants with fewer precancerous growths, researchers said.
- Scientists are advancing experimental vaccines designed to intercept colon cancer in people with Lynch syndrome, as Dr. Eduardo Vilar-Sanchez of the Anderson Cancer Center expects a larger study to begin early next year.
- Roughly 1 million Americans carry Lynch syndrome, a faulty DNA mismatch-repair gene disorder that raises lifetime colorectal cancer risk to as high as 80 percent, compared to around 5 percent for the general population.
- In a recent study, 44 Lynch carriers tested a vaccine from Swiss biotech Nouscom targeting 209 abnormal protein markers, boosting tumor-fighting T cells and resulting in fewer precancerous growths and no advanced polyps.
- Houston physician Dr. Stacy Norton, a study participant who lost family members to cancer, said the vaccine offers hope, noting, "perhaps they won't have to have a colonoscopy every single year for the rest of their lives."
- Additional vaccine candidates are under development, including a Moderna mRNA vaccine in Britain and a California-based ImmunityBio Tri-Ad5 shot being compared against placebo, aiming to train the immune system to recognize cancer markers.
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31 Articles
Testing is underway on vaccines to intercept brewing colon cancer before it takes root
A shot to prevent cancer? Scientists are testing vaccines designed to stop certain tumors before they form.
Colon Cancer Prevention Vaccines Enter Testing to Stop Tumors Before They Start
Internewscast Journal Internewscast HOUSTON, Texas — Dr. Stacy Norton was just 7 when colon cancer… This Post: Colon Cancer Prevention Vaccines Enter Testing to Stop Tumors Before They Start first appeared on Internewscast Journal
New Vaccines May Help Ward Off Colon Cancer
Dr. Stacy Norton was only 7 years old when her mother died of colon cancer, one of several family members struck by aggressive tumors at unusually young ages. Decades later, Norton rolled up her sleeve to help test if a new kind of vaccine might protect her and her own...
Testing underway for colon cancer vaccine
According to a report from CNN, based on Associated Press coverage, researchers are advancing experimental vaccines designed to intercept colon cancer at its earliest stages in people carrying a high-risk inherited condition. The effort targets Lynch syndrome, a genetic disorder that dramatically elevates the odds of developing aggressive colorectal tumors and other cancers, often at […]
Scientists Are Testing Vaccines That Could Head Off Inherited Colon Cancer
Scientists are testing vaccines designed to prevent Lynch syndrome-related colon cancer from forming, with early results published in Nature Medicine. The post Scientists Are Testing Vaccines That Could Head Off Inherited Colon Cancer appeared first on The Sun Papers.
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