Nicotinamide Riboside Shows Promise in Treating Werner Syndrome Symptoms

Vitamin B3 derivative improves health and complications in rare premature aging disorder in clinical trial

Werner syndrome (WS), a rare genetic disorder that causes accelerated aging. From their twenties, patients develop gray hair, hair loss, cataracts, diabetes, and other age-related conditions normally seen in the elderly. Additionally, patients develop severe and untreatable skin ulcers, often requiring limb amputation, and face early death from cardiovascular diseases or cancer. This debilitating condition, which affects approximately nine per m…

Telomir Pharmaceuticals Announces Telomir-1 Resets the Body's Epigenetic Clock, Reverses DNA Methylation, and Restores Youthful Gene Regulation in an Ultra-Rare Accelerated Aging Animal Model of Werner Syndrome

Treatment restored gene control, extended telomere length beyond healthy levels, reversed muscle and weight loss, reduced oxidative stress, and resulted in 100% survival - highlighting Telomir-1's potential to reverse key hallmarks of aging

Nicotinamide riboside shows promise in treating Werner syndrome symptoms

Werner syndrome (WS) is a rare genetic disorder that causes premature aging and serious complications. In the first clinical trial of its kind, researchers from Japan with the company Niagen Bioscience, investigated the effects of nicotinamide riboside (NR), a vitamin B3 derivative, in patients with WS.

EXCLUSIVE: Telomir Pharmaceuticals Lead Drug Shows Promising Signs In Animal Study For Rare Premature Aging Disorder - Telomir Pharmaceuticals (NASDAQ:TELO)

Telomir-1 boosted telomere length, restored weight and muscle, and cut oxidative stress in a preclinical Werner Syndrome animal model.

Trial into rare genetic disease Werner syndrome reports promising results - Pharmafile

Researchers at Chiba University, Japan, alongside Niagen Bioscience, have reported successful results from the world’s first trial of nicotinamide riboside (NR), vitamin B3 derivative, for the treatment of Werner syndrome (WS), a rare genetic disorder. The study found that it enhances cardiovascular, skin and kidney health in patients, offering treatment potential for a disease which […] The post Trial into rare genetic disease Werner syndrome r…

Breakthrough Advances Bring New Hope to Werner Syndrome Patients

Werner syndrome (WS) represents a profoundly rare genetic disorder characterized by an accelerated aging phenotype, afflicting individuals with premature onset of conditions typically observed in elderly populations. Manifesting usually in individuals’ twenties, this syndrome rapidly progresses to cause hallmark symptoms such as graying hair, alopecia, cataracts, diabetes mellitus, and an array of degenerative changes across multiple organ syste…