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Universal mRNA Vaccine Eradicates Tumors in Mice nd Advances Toward Human Trials

ALACHUA COUNTY, FLORIDA, JUL 18 – Researchers at the University of Florida aim to create an off-the-shelf cancer vaccine that activates immune responses like viral infections, with some mouse models showing complete tumor elimination.

  • Last year, University of Florida researchers developed an experimental mRNA cancer vaccine, uniquely stimulating immune responses as if fighting a virus.
  • Prior work in mRNA technology led to the development of an experimental vaccine that stimulates immune responses, explaining the scientific rationale.
  • Animal studies revealed that in mouse models, the vaccine triggered a strong anticancer response, with some tumors completely eradicated, even without targeting specific cancer types.
  • Sayour noted the vaccine's broad potential as an alternative to surgery, radiation, and chemotherapy, highlighting its implications for treatment-resistant tumors.
  • Next steps include refining the vaccine formulations and moving toward human clinical trials, bringing us closer to a universal cancer vaccine with broad therapeutic potential.
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Lean Left

A new vaccine could pave the way for universal cancer vaccinations that "incite" the immune system against tumours in affected patients

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Center

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fiercebiotech.com broke the news in on Wednesday, July 16, 2025.
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