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Chronic Gut Infection Could Play a Role in Alzheimer's Development

UNITED STATES, JUL 8 – Researchers identify a biologically distinct Alzheimer's subtype linked to cytomegalovirus gut infection affecting up to 45% of patients and explore antiviral treatment potential.

  • Scientists collaborating with institutions in Arizona have identified a connection between long-term gut infection by cytomegalovirus and the onset of Alzheimer's disease in certain individuals.
  • This study arose from recent advances showing persistent infections may contribute to neurodegeneration and immune changes seen in Alzheimer's progression.
  • The virus may linger in the gut and travel via the vagus nerve to the brain, creating a unique Alzheimer's subtype affecting 25% to 45% of patients.
  • Dr. Ben Readhead stated that their research has identified a distinct biological form of Alzheimer's disease, which could be present in roughly one-quarter to nearly half of those diagnosed, opening up new possibilities for treatment.
  • If confirmed, these findings could enable use of antiviral drugs and biomarker blood tests to improve diagnosis and personalize Alzheimer's prevention and treatment.
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PsyPost broke the news in on Tuesday, July 8, 2025.
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