Chronic Gut Infection Could Play a Role in Alzheimer's Development
UNITED STATES, JUL 8 – Researchers identify a biologically distinct Alzheimer's subtype linked to cytomegalovirus gut infection affecting up to 45% of patients and explore antiviral treatment potential.
- Scientists collaborating with institutions in Arizona have identified a connection between long-term gut infection by cytomegalovirus and the onset of Alzheimer's disease in certain individuals.
- This study arose from recent advances showing persistent infections may contribute to neurodegeneration and immune changes seen in Alzheimer's progression.
- The virus may linger in the gut and travel via the vagus nerve to the brain, creating a unique Alzheimer's subtype affecting 25% to 45% of patients.
- Dr. Ben Readhead stated that their research has identified a distinct biological form of Alzheimer's disease, which could be present in roughly one-quarter to nearly half of those diagnosed, opening up new possibilities for treatment.
- If confirmed, these findings could enable use of antiviral drugs and biomarker blood tests to improve diagnosis and personalize Alzheimer's prevention and treatment.
13 Articles
13 Articles


Research has shown a link between infectious agents that have been hiding in the body for years and the onset of a form of dementia called Alzheimer's disease, but could it also be part of a cure for it?
Chronic gut infection could play a role in Alzheimer's development
Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people.

The connection could explain why strangely drugs against diabetes help prevent dementia and Alzheimer's disease.
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A neuroimaging study of older adults found that those who spent more time sitting tended to have worse episodic memory. They also showed faster reductions in hippocampal volume over the 7-year study period and experienced more rapid declines in cognitive processing speed. The findings were published in the Journal of the Alzheimer’s Association. Sedentary behavior refers to activities that involve sitting or lying down and require very low energ…
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