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Study Casts Doubt on Use of Beta Blockers Post-Heart Attack, Especially for Women

The study found women with normal heart function taking beta-blockers after uncomplicated heart attacks were three times more likely to die, sparking debate over treatment guidelines.

  • On Aug. 30, the National Centre for Cardiovascular Research in Spain reported that beta-blockers do not reduce death, second heart attack, or heart failure risk in many survivors; the Ministry of Health urged patients not to stop use without consulting doctors.
  • Dr. Borja Ibáñez said the practice dates back more than four decades, with beta‑blockers standard for over 80% of uncomplicated myocardial infarction patients, studied in 8,438 patients across 109 healthcare centers.
  • For women with normal EF, the trial found those with left ventricular ejection fraction above 50 percent had nearly 3% higher death risk on beta-blockers, especially high-dose recipients.
  • Researchers warn that the study could affect guideline recommendations as Spanish cardiology researchers estimate 1.2 million people in Spain may take unnecessary beta-blockers, prompting potential changes to international clinical guidelines.
  • Health officials urged caution as Spain's Ministry of Health and National Centre for Cardiovascular Research in Spain clash over beta‑blocker guidelines, with patients advised to consult their doctors before changes due to roles in arrhythmia and high blood pressure.
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Study Casts Doubt on Use of Beta Blockers Post-Heart Attack, Especially for Women

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·Missoula, United States
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A new study calls into question the routine use of beta-blockers after a heart attack, showing few significant benefits and a potential increase in adverse events, particularly in women. Cardiologist Dr. Olivier Hoffman sheds light on these findings.

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U.S. News broke the news in New York, United States on Wednesday, September 3, 2025.
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