Snora54 Negatively Regulates Self-Renewal of Intestinal Stem Cells and Gut Regeneration via Suppression of Notch2 Signaling
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Snora54 Negatively Regulates Self-Renewal of Intestinal Stem Cells and Gut Regeneration via Suppression of Notch2 Signaling
Investigators identified a small nucleolar RNA (Snora54) that was highly expressed in the nucleolus of intestinal stem cells (ISCs). Snora54 knockout enhanced the self-renewal capacity of ISCs and intestinal regeneration. [Science Advances] Full Article
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