New Molecular Imaging Agent Shows High Accuracy in Detecting Liver Cancer

New study from VCU Massey Center sheds light on liver cancer’s genetic roots

RICHMOND, Va. (WRIC) -- Researchers from Virginia Commonwealth University's (VCU) Massey Comprehensive Cancer Center have discovered a new genetic target that could possibly shape the future of treatment for liver cancer. According to the university, Hepatocellular carcinoma (HCC), is a common type of liver cancer and the third-leading cause of cancer-related deaths around the world -- but thanks to research from Devanand Sarkar, M.B.B.S., Ph.D …

New molecular imaging agent shows high accuracy in detecting liver cancer

A novel molecular imaging agent targeting glypican-3 (GPC3) has demonstrated high sensitivity and specificity in detecting hepatocellular carcinoma (HCC), including tumors smaller than one centimeter, according to results from a pilot clinical study.

GPC-Targeting Imaging Agent May Improve Liver Cancer Detection

A novel molecular imaging agent targeting glypican-3 (GPC3) has high sensitivity and specificity in detecting hepatocellular carcinoma (HCC), including tumors smaller than one centimeter, according to results from a Chinese pilot clinical study. HCC is the sixth most common cancer and the third leading cause of cancer-related deaths globally, accounting for 75–85% of all primary liver cancers. The agent, 68Ga-aGPC3-scF, was shown to be safe, wel…

Ultrasound Molecular Imaging Enhances High-Intensity Focused Ultrasound Ablation on Liver Cancer With B7-H3-Targeted Microbubbles

ABSTRACT Background High-intensity focused ultrasound (HIFU) is a promising minimally invasive treatment for liver cancer; however, its efficacy is often limited by the attenuation of ultrasonic energy. This study investigates the effectiveness of B7-H3-targeted microbubbles (T-MBs) in enhancing HIFU ablation of liver cancer and explores their potential for clinical translation. Methods T-MBs and isotype control microbubbles (I-MBs) were synthes…

World-class imaging scanner arrives in Scotland | News | The University of Edinburgh

World-class imaging scanner arrives in Scotland jconway3 Tue, 24/06/2025 - 11:15 Scotland’s first total-body scanner is set to accelerate drug development and diagnosis for patients, with scans up to 40 times more sensitive than existing machines. The Positron Emission Tomography (PET) scanner will capture images of patients’ entire bodies 10 times faster, in more detail and using less radiation than existing scanners.The scanner, co-managed by…

New ImmunoPET Tracer Boosts Early Liver Cancer Detection

A groundbreaking development in the early detection of hepatocellular carcinoma (HCC) has emerged from the halls of Wuhan Union Hospital at Huazhong University of Science and Technology. Researchers have unveiled a novel molecular imaging agent, designated 68Ga-aGPC3-scFv or XH06, capable of precisely targeting glypican-3 (GPC3), a cell surface receptor that is prevalently overexpressed in HCC tumors. This advancement promises to revolutionize t…