Single Antibody Causes a Rare but Dangerous Reaction to Widely-Used Blood Thinner
Researchers found a single monoclonal antibody causes heparin-induced thrombocytopenia, affecting 1% of heparin-treated patients and causing life-threatening clots in nearly half, enabling better diagnosis.
5 Articles
5 Articles


Single antibody causes a rare but dangerous reaction to widely-used blood thinner
Researchers at McMaster University have discovered that a rare but dangerous reaction to a widely used blood thinner is caused by a single antibody – overturning decades of medical misunderstanding and opening the door to more precise ways of diagnosing and treating this medical complication.
Single antibody may be responsible for life-threatening reaction to common blood thinner
Researchers at McMaster University have discovered that a rare but dangerous reaction to a widely used blood thinner is caused by a single antibody—overturning decades of medical misunderstanding and opening the door to more precise ways of diagnosing and treating this medical complication.
Scientists Discover Single Antibody Triggering Severe Reaction to Widely
In a groundbreaking discovery set to revolutionize hematology and immunology, researchers at McMaster University have uncovered that heparin-induced thrombocytopenia (HIT) is driven by a single monoclonal antibody, challenging decades of prevailing scientific thought. This rare but severe immune reaction to heparin, a blood thinner widely used in hospitals worldwide, causes dangerous blood clots in affected patients and has long puzzled clinicia…
Researchers Identify Single Antibody Behind Life-Threatening Reaction to Common Blood Thinner
Researchers at McMaster University have discovered that a rare but dangerous reaction to a widely used blood thinner is caused by a single antibody – overturning decades of medical misunderstanding. The findings published on Sept. 3, 2025 in the New England Journal of Medicine.
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