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Semaglutide Modestly Reduces Epigenetic Age in Overweight Individuals

Summary by fightaging.org
There is some debate over whether GLP-1 receptor agonist drugs such as semaglutide can affect mechanisms relevant to aging independently of weight loss. GLP-1 receptors are present in many organs, including the brain, so it is not unreasonable to think that other outcomes may result from GLP-1 receptor agonism over and above reduced appetite and calorie intake. But do those outcomes slow aging to a meaningful degree in comparison to the effects …
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fightaging.org broke the news in on Wednesday, August 13, 2025.
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