Scientists trace social challenges in autism to specific brain circuit
- Scientists at the University of Geneva found that social orientation deficits are seen in children with autism spectrum disorders from their first year of life.
- Nada Kojovic developed a non-sedation MRI protocol for children, achieving quality images in over 90% of the participants.
- The research identified a communication pathway defect between brain structures that hinders attention redirection, crucial for decoding social interactions.
- In children who show a delay, cognitive difficulties are a consequence of a lack of understanding of social interactions.
7 Articles
7 Articles
Epigenomic signatures reveal mechanistic clues and predictive markers for autism spectrum disorder
Autism spectrum disorder (ASD) comprises a heterogeneous group of neurodevelopmental outcomes in children with a commonality in deficits in social communication and language combined with repetitive behaviors and interests. The etiology of ASD is heterogeneous, as several hundred genes have been implicated as well as multiple in utero environmental exposures. Over the past two decades, epigenetic investigations, including DNA methylation, have e…
Autism: The neural origin of the social bond
From birth, human survival depends on the ability to engage with others. This ability, which is essential for development, seems to be impaired very early on in children with autism spectrum disorders (ASD), who show limited interest in social stimuli from their first year of life.
Early Brain Circuit Disruption Linked to Autism Social Challenges
New research has uncovered a disrupted brain communication pathway in children with autism that impairs their ability to quickly shift attention—an essential skill for social interaction. This discovery was made by studying both children with autism and genetically modified mice lacking the Shank3 gene, a common cause of ASD.
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