Study Creates Genetic Roadmap of How HIV Virus Interacts with Human Cells

Study creates genetic roadmap of how HIV virus interacts with human cells

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

Scientists map how HIV hijacks human cells—and how cells can fight back

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body. Yet, even after decades of research on how the virus replicates and persists, researchers still haven't solved the mystery of exactly which human genes influence HIV infection.

Scientists Map Human Genes That Control HIV Infection Dynamics

The human immunodeficiency virus (HIV), which is the cause of AIDS, is a master of deception, using just nine genes to hijack the complex cellular machinery of the human body.

CRISPR Screens Map Human T‑Cell Genes That Promote or Block HIV Infection

Genome‑wide CRISPR screens in primary human T cells reveal human genes that promote or block HIV infection, uncovering potent antiviral factors like PI16 and PPID.

Scientists Chart HIV’s Invasion of Human Cells—and Uncover How Cells

Scientists at Gladstone Institutes and UCSF have unveiled a groundbreaking genetic roadmap elucidating how HIV exploits human cells, providing unprecedented insight into the virus’s interaction with the immune system. Despite nearly four decades of research, the complex interplay between HIV and the host’s cellular machinery remained largely elusive—until now. By deploying advanced CRISPR gene-editing technology […]