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What Your Genes Can, and Cannot, Tell Us About Your Personality

Researchers identified more than 1,260 common genetic variants tied to the Big Five, but said genetics explains only 5% to 10% of personality differences.

  • On September 2, researchers published a study in Nature identifying 1,260 genetic variants linked to the Big Five personality traits, offering new insights into biological factors contributing to human behavior.
  • Psychologist Elliot Tucker-Drob and colleagues combined 46 study cohorts involving more than 1.1 million people to overcome previous difficulties in untangling personality's genetic component using large population databases.
  • The analysis identified 1,260 genetic variants, including 824 previously unknown, explaining roughly 4.8% to 13.3% of personality variation and correlating with health, psychiatric disorders, and life outcomes.
  • Princeton University sociologist Dalton Conley noted the findings challenge theories linking neuroticism to serotonin, while epidemiologist Michel Nivard stressed the data provides population-level insights rather than individual personality predictions.
  • Researchers stress that personality emerges from a mixture of genetics and environment, with genetic variants representing only a small proportion of overall personality variation despite their measurable associations.
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More than a million genomes helped identify DNA variants linked to extroversion, kindness, neuroticism, and other traits. Researchers measured how these traits influenced people’s way of life.

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A person's character is shaped by both heredity and life experiences. A recent study involving data from more than a million people revealed over a thousand gene variants linked to personality traits, yet they explain only a small portion of the differences between people.

·Tallinn, Estonia
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NewsNation broke the news in Chicago, United States on Thursday, September 3, 2026.
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