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Sanofi to acquire hepatitis B vaccine maker Dynavax for $2.2 billion

Sanofi will acquire Dynavax for $2.2 billion to add the adult hepatitis B vaccine HEPLISAV-B and shingles vaccine candidate Z-1018 to its portfolio, targeting a large unvaccinated adult population.

  • Sanofi agreed to acquire Dynavax Technologies Corporation for $2.2 billion, paying $15.50 per share in cash on Dec. 24, 2025.
  • Sanofi is pursuing the deal to strengthen adult immunization by adding Dynavax's marketed vaccine and pipeline, including Z-1018 which showed comparable efficacy to Shingrix in recent trials; this is Sanofi's second vaccines buy this year after the Vicebio acquisition.
  • HEPLISAV-B's two-dose, one-month regimen differentiates it from competitors, with Dynavax reporting $268.4 million in 2024 HEPLISAV-B sales and a 46% market share .
  • Markets reacted immediately, with Dynavax shares jumping more than 40% in pre-market trading on Wednesday, while the tender offer has not yet commenced and shareholders are urged to review tender offer materials and related SEC filings.
  • Sanofi plans to fund the acquisition with available cash, with completion subject to the Hart-Scott-Rodino waiting period and foreign regulatory filings, and it said this would not affect its 2025 guidance.
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Sanofi to acquire hepatitis B vaccine maker Dynavax for $2.2 billion

Sanofi will buy U.S. vaccines company Dynavax Technologies for around $2.2 billion (1.9 billion euros), the French drugmaker said on Wednesday, a deal that will give it access to an approved hepatitis B vaccine.

·United Kingdom
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stocktitan.net broke the news in on Wednesday, December 24, 2025.
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