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Safe focused ultrasound-mediated blood-brain barrier opening is driven primarily by transient reorganization of tight junctions
Focused ultrasound (FUS) with microbubbles opens the blood-brain barrier (BBB) for targeted drug delivery into the brain. How brain endothelial cells (BECs) respond to either low acoustic pressures known to open the BBB transiently, or high pressures that cause brain damage, is incompletely chara...
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