US EditionRNA-editing enzyme ADAR1 may be new Parkinson's target
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RNA-editing enzyme ADAR1 may be new Parkinson's target
The dysregulation of RNA editing within astrocytes (neuron-supporting cells) seems to induce chronic inflammation and ultimately contributes to the loss of nerve cells in people with Parkinson’s disease, according to a recent study. This dysregulation is triggered by alpha-synuclein clumping, which is a characteristic feature of Parkinson’s. RNA editing refers to changes in the sequence of messenger RNA — the intermediate molecule derived from D…
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