US EditionRetiring NHS England boss says cancer treatment on ‘cusp of golden era’
ENGLAND, JUL 14 – Professor Sir Stephen Powis warns of unequal cancer care quality and urges investment in supportive oncology as genetics drive more personalized treatments and survival improves.
- Sir Stephen Powis, outgoing medical director of NHS England, stated cancer treatment is at the cusp of a golden era transforming care across the UK.
- This optimism follows advances in immunotherapy research led by Sophie Paczesny that revealed and targeted a key leukemia resistance pathway involving IL-33 and IL1RL1.
- Paczesny’s team developed a bispecific antibody immunotherapy that kills leukemia cells and disrupts their protective immune environment without major side effects.
- "Our treatment is an off-the-shelf drug," Paczesny said, emphasizing its lower cost and easier production compared to customized therapies like CAR-T cell treatment.
- Despite these innovations, NHS cancer treatment faces challenges including falling performance in timely care and upcoming doctor strikes, highlighting a need for further investment and reforms.
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whitchurchherald.co.uk
hampshirechronicle.co.ukRetiring NHS England boss says cancer treatment on 'cusp of golden era'
Many cancers no longer 'a death sentence' as treatment on 'cusp of golden era', NHS England medical director says
Sir Stephen Powis said the number of those living longer with the disease and surviving will continue to increase, as he compared the progress made in cancer treatment to the success in developing treatment for HIV since he qualified as a doctor 40 years ago.
Fighting leukemia by breaking a hidden cell loop
Researchers at MUSC Hollings Cancer Center have identified a signaling loop involved in the growth and persistence of leukemia cells—and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival. The findings, published in Nature Communications, offer new hope for treating and preventing cancer.
Evening Standard
Retiring NHS England boss says cancer treatment on ‘cusp of golden era’
Professor Sir Stephen Powis said he expects drugs harnessing the body’s immune system to fight the disease will bring ‘great advances in survival’.
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