Impaired Blood Flow Alters Immunity and Fuels Tumor Progression
5 Articles
5 Articles
A study in animal models showed that blood circulation restriction causes profound changes in the immune system and promotes tolerance to malignant cells
Impaired Blood Flow Accelerates Tumor Growth by Aging the Immune System
A groundbreaking study from NYU Langone Health has revealed a critical connection between impaired blood flow and accelerated cancer progression, shedding new light on how vascular health influences tumor growth. The research, published on August 19, 2025, in JACC CardioOncology, demonstrates that ischemia—an obstruction of blood flow caused by artery narrowing—not only affects cardiovascular outcomes […]
Ischemia Drives Breast Cancer Growth in Mice by Weakening Immunity
Cutting off blood flow can prematurely age the bone marrow, weakening the immune system’s ability to fight cancer, according to a new study from NYU Langone Health. The team’s preclinical study showed that peripheral ischemia—restricted blood flow in the arteries in the legs—caused breast tumors in mice to grow at double the rate seen in mice without restricted flow. The findings build on a 2020 study from the same team, which reported ischemia …
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