Researchers Uncover Hidden Individual Differences in Viral Infections

Researchers Uncover Hidden Individual Differences in Viral Infections

An international team of researchers has developed a quantitative approach to reveal hidden, cell-by-cell differences in how viruses infect and trigger cell lysis. The work addresses a biological problem that has remained open for more than eight decades: the internal sequence of events inside a single infected cell is difficult to measure directly, yet the timing of lysis and the resulting burst size determine viral fitness. For years, virology…