Researchers Link Gene Variant to Aggressive Prostate Cancer Risk

A Novel lncRNA HUDRPC Suppresses Ferroptosis via the DDX5/DDIT3 Pathway to Promote Docetaxel Resistance in Prostate Cancer

The authors functionally characterized a novel docetaxel resistance-associated lncRNA in prostate cancer. They identified an uncharacterized lncRNA, termed HUDRPC, which was significantly upregulated in resistant cells and patient-derived tumor tissues. [Cancer Letters] Abstract

Researchers Link Gene Variant to Aggressive Prostate Cancer Risk

Study findings suggest adding the CDK12 variant to hereditary screening panels could help identify men at risk for early-onset disease. A gene variant that can be passed through families may increase the risk of developing early, aggressive prostate cancer, according to researchers at the University of Washington School of Medicine and the University of British Columbia. The study, published in the journal Cancer Discovery, suggests that the gen…