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Study Finds Space Travel Rapidly Accelerates Biological Aging, Raising Mars Mission Concerns

  • A study led by UC San Diego, published on September 4, 2025, found that exposure to spaceflight speeds up the aging process in the blood-forming and immune-related stem and progenitor cells aboard the International Space Station.
  • The research expands on the 2015-2016 NASA Twins Study and incorporates insights from a comprehensive body of 44 studies published by a leading consortium focused on aerospace medicine and biology, emphasizing the impact of space-related stressors such as microgravity and radiation.
  • The team used AI-driven nanobioreactors on four SpaceX ISS resupply missions to track real-time changes showing HSPCs lost regeneration ability, incurred DNA damage, and activated normally silent genome regions.
  • Twyman Clements, president of Space Tango, expressed enthusiasm about sharing the significant research findings with the broader scientific and space exploration communities, highlighting the collaborative nature of the project.
  • The findings have important consequences for astronaut well-being and enhance our understanding of aging and cancer on Earth, leading to planned follow-up missions on the ISS and development of strategies to preserve the integrity of stem cells during prolonged space travel.
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Stem cells age faster in space, study reveals

Spaceflight makes certain human stem cells age faster, a study finds, furthering the understanding of the possible effects of space exploration on the human body.

·Atlanta, United States
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Vox broke the news in United States on Wednesday, September 3, 2025.
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