'Master Control Switch' Protein that Heightens Neurodegenerative Disease Offers New Treatment Target

'Master control switch' protein that heightens neurodegenerative disease offers new treatment target

UT Southwestern Medical Center scientists have identified a protein that appears to act as a master control switch for reactive gliosis, a prominent feature of many neurodegenerative diseases that is thought to contribute to their pathology. The researchers' findings, published in Neuron, could eventually lead to new treatments for Alzheimer's, Parkinson's, and Huntington's diseases and other neurodegenerative conditions.

Protein Identified as Master Control Switch for Reactive Gliosis Linked to Neurodegenerative Diseases

Scientists at UT Southwestern Medical Center have ident […]

Research Untangles Role of Stress Granules in Neurodegenerative Disease

Scientists at St. Jude Children's Research Hospital and Washington University in St. Louis found that stabilizing stress granules suppresses the effects of ALS-causing mutations, correcting previous models that imply stress granules promote amyloid formation.