US EditionR-Loop DNA Provokes Chronic Inflammation via cGAS/STING
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R-Loop DNA Provokes Chronic Inflammation via cGAS/STING
Stretches of nuclear DNA can adopt a broad range of transient structural forms, guided by the complex feedback loops of epigenetic marks, decorating molecules added to and removed from DNA. Epigenetics as a form of control over gene expression is all a matter of structure: which regions are packaged up and inaccessible, which are accessible. Other processes can also have their effects on local structure of the DNA, however. Some of the resulting…
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