Psychedelic control of neuroimmune interactions governing fear

Psychedelics May Reduce Chronic Pain and Related Opioid Use

Recent research indicates that the use of psychedelics has the potential to significantly reduce the experience of chronic pain, as well as associated substance use.

LSD Tweaked to Harness Therapeutic Power for Mental Health Without Hallucinogenic Effects

With its ability to aid in enhancing neuroplasticity, the famous hallucinogenic compound LSD has been theorized as a treatment option for neurological disorders like cognitive decline and schizophrenia. One wouldn’t want to dose a schizophrenic with LSD, but following the synthesis of a new molecule based on LSD at a laboratory in California, they may […] The post LSD Tweaked to Harness Therapeutic Power for Mental Health Without Hallucinogenic …

Unlawful, often considered dangerous, substances that are hallucinogenic or alter the state of consciousness, such as LSD or MDMA, are, however, the subject of renewed interest in researchers. Clinical trials are increasing, particularly in France, to evaluate their effectiveness on various mental health disorders and addictions.

Psilocybin and MDMA May Silence Fear at Its Roots, Study Finds

Researchers at Mass General Brigham discovered that interactions between immune cells and brain cells play a key role in triggering fear responses. However, treatments with psychedelics such as MDMA and psilocybin may help reverse these effects. Researchers at Mass General Brigham have discovered that interactions between the immune system and brain cells play a critical [...]

Psychedelic control of neuroimmune interactions governing fear

Neuroimmune interactions—signals transmitted between immune and brain cells—regulate many aspects of tissue physiology1, including responses to psychological stress2–5, which can predispose individuals to develop neuropsychiatric diseases6–9. Still, the interactions between haematopoietic and brain-resident cells that influence complex behaviours are poorly understood. Here, we use a combination of genomic and behavioural screens to show that as…

Psychedelic use linked to shifts in sexuality, gender expression, and relationship dynamics, study finds

A new study published in The Journal of Sex Research highlights how psychedelic experiences may shape people’s sexualities, gender expressions, and intimate relationships. Surveying 581 individuals who had used psychedelics, researchers found that a majority reported both short-term and long-term changes related to sexuality and relationships, including heightened attraction to partners, increased openness, and altered experiences of gender iden…