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Prices for new US drugs doubled in 4 years as focus on rare disease grows

  • U.S. Prices for newly launched drugs more than doubled between 2021 and 2024, reaching a median of over $370,000 last year.
  • This rise reflects increased development of therapies for rare diseases, which are often priced high due to small patient populations.
  • In 2024, 72% of new drugs targeted orphan diseases affecting fewer than 200,000 Americans, with over 40% addressing oncology conditions.
  • Record prices include Lenmeldy at $4.25 million for a one-time gene therapy launched in 2023, while Pfizer's $3.5 million Beqvez therapy was withdrawn due to low demand.
  • The trend suggests sustained high prices until reducing development costs, as stakeholders emphasize these drugs’ value despite concerns about overall affordability.
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U.S. News broke the news in New York, United States on Thursday, May 22, 2025.
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