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Prediction of mild cognitive impairment progression using time-sensitive multimodal biomarkers

Summary by Science
Abstract Alzheimer’s disease (AD) develops silently for years before symptoms emerge, making early identification of at-risk individuals essential for prevention trials and early intervention. We tested whether combining neurophysiological, imaging, and blood biomarkers improves prediction of progression to mild cognitive impairment (MCI) in cognitively unimpaired older adults with a family history of AD ( n = 102; 31 progressors; mean follow-up…

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Science broke the news in Washington, United States on Wednesday, August 12, 2026.
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