Post-Thrombectomy Alteplase Linked to Better Stroke Outcomes
The CHOICE2 trial showed intra-arterial alteplase after thrombectomy improved excellent 90-day stroke recovery by 15 percentage points, though safety results varied.
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8 Articles
Researchers found a way to improve the results of surgery for an ischemic Vascular Case (AVC) — that caused by a blockade of an artery, preventing the full operation of the brain. The idea of having a better result in thrombectomy (the name given to surgery) is to combine it with the rapid infusion of a known and common medicine in the treatment of AVC called Alteplase, used to resolve colleagues. Both the operation and the medicine are released…
Post-thrombectomy alteplase linked to better stroke outcomes
Giving the clot-busting medication alteplase at the site of a blocked brain artery after blood clot removal may increase the number of patients who fully recover, according to preliminary late-breaking science presented at the American Stroke Association's International Stroke Conference 2026.
Stroke Trial Tips Scale Further to Favor Intra-Arterial Lytic After EVT
(MedPage Today) -- NEW ORLEANS -- A stronger case could be made for intra-arterial (IA) alteplase after successful mechanical thrombectomy based on more randomized data, this time the CHOICE-2 trial from Spain. In acute ischemic stroke patients...
Late-Breaking CHOICE 2 Data Indicate Alteplase Displayed Improved Stroke Recovery | NeurologyLive - Clinical Neurology News and Neurology Expert Insights
Adding intra-arterial alteplase after successful endovascular thrombectomy significantly improved 90-day functional outcomes in patients with large-vessel acute ischemic stroke, according to late-breaking data from the phase 3 CHOICE2 trial.
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